INDICATIONS

REBLOZYL® (luspatercept-aamt) is indicated for the treatment of anemia in adult patients with beta thalassemia who require regular red blood cell (RBC) transfusions.

REBLOZYL® (luspatercept-aamt) is indicated for the treatment of anemia without previous erythropoiesis stimulating agent use (ESA-naïve) in adult patients with very low- to intermediate-risk myelodysplastic syndromes (MDS) who may require regular red blood cell (RBC) transfusions.

REBLOZYL® (luspatercept-aamt) is indicated for the treatment of anemia failing an erythropoiesis stimulating agent and requiring 2 or more red blood cell (RBC) units over 8 weeks in adult patients with very low- to intermediate-risk myelodysplastic syndromes with ring sideroblasts (MDS-RS) or with myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T).

REBLOZYL is not indicated for use as a substitute for RBC transfusions in patients who require immediate correction of anemia.

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SUPPORT AND RESOURCES: ACCESS AND FINANCIAL RESOURCES

Authorized distributors

REBLOZYL can only be purchased through authorized distributors for administration in physician offices, hospital outpatient facilities, institutions, Veterans Affairs, and the Department of Defense. The following distributors are authorized to sell REBLOZYL and are able to service qualified accounts.

Authorized distributor network

PHYSICIAN OFFICES
Authorized Distributor Phone/Fax Website
Cardinal Health Specialty Pharmaceutical Distribution
Mon-Fri, 7:00 AM-6:00 PM CT
1-877-453-3972 specialtyonline.cardinalhealth.com
CuraScript Specialty Distribution
Mon-Fri, 8:00 AM-7:00 PM ET
1-877-599-7748 www.curascriptsd.com
McKesson Specialty Health
Mon-Fri, 7:00 AM-7:00 PM CT
1-800-482-6700 mscs.mckesson.com
Morris & Dickson Specialty
Mon-Fri, 8:00 AM-6:00 PM CT
1-800-710-6100
1-318-524-3096 (Fax)
www.mdspecialtydist.com
Oncology Supply
Mon-Fri, 8:00 AM-7:00 PM CT
1-800-633-7555 www.oncologysupply.com
HOSPITALS AND INFUSION CENTERS
Authorized Distributor Phone/Fax Website
ASD Healthcare
Mon-Thurs, 7:00 AM-6:30 PM CT;
Friday, 7:00 AM-6 PM CT
1-800-746-6273
1-800-547-9413 (Fax)
www.asdhealthcare.com
Cardinal Health Specialty Pharmaceutical Distribution
Mon-Fri, 7:00 AM-6:00 PM CT
1-866-677-4844
1-614-553-6301 (Fax)
orderexpress.cardinalhealth.com
DMS Pharmaceutical Group, Inc.
Mon-Fri, 8:30 AM-5:00 PM CT
1-877-788-1100
1-847-518-1105 (Fax)
www.dmspharma.com
McKesson Plasma and Biologics
Mon-Fri, 8:00 AM-6:30 PM CT
1-877-625-2566
1-888-752-7626 (Fax)
connect.mckesson.com
PUERTO RICO HOSPITALS AND CLINICS
Authorized Distributor Phone/Fax Website
Cardinal Puerto Rico (Borschow) 1-787-625-4200 orderexpress.cardinalhealth.com
Cesar Castillo, Inc. 1-787-641-5242 (Hospitals)
1-787-641-5082 (Specialty Pharmacies)
1-787-999-1614 (Fax)
www.facilfarmaciacci.com
PHYSICIAN OFFICES
Authorized Distributor Phone/Fax/Website
Cardinal Health Specialty Pharmaceutical Distribution
Mon-Fri, 7:00 AM-6:00 PM CT
1-877-453-3972
specialtyonline.
cardinalhealth.com
CuraScript Specialty Distribution
Mon-Fri, 8:00 AM-7:00 PM ET
1-877-599-7748
www.curascriptsd.com
McKesson Specialty Health
Mon-Fri, 7:00 AM-7:00 PM CT
1-800-482-6700
mscs.mckesson.com
Morris & Dickson Specialty
Mon-Fri, 8:00 AM-6:00 PM CT
1-800-710-6100
1-318-524-3096 (Fax)
www.mdspecialtydist.com
Oncology Supply
Mon-Fri, 8:00 AM-7:00 PM CT
1-800-633-7555
www.oncologysupply.com
HOSPITALS AND INFUSION CENTERS
Authorized Distributor Phone/Fax/Website
ASD Healthcare
Mon-Thurs, 7:00 AM-6:30 PM CT;
Friday, 7:00 AM-6 PM CT
1-800-746-6273
1-800-547-9413 (Fax)
www.asdhealthcare.com
Cardinal Health Specialty Pharmaceutical Distribution
Mon-Fri, 7:00 AM-6:00 PM CT
1-866-677-4844
1-614-553-6301 (Fax)
cardinalhealth.com
DMS Pharmaceutical Group, Inc.
Mon-Fri, 8:30 AM-5:00 PM CT
1-877-788-1100
1-847-518-1105 (Fax)
www.dmspharma.com
McKesson Plasma and Biologics
Mon-Fri, 8:00 AM-6:30 PM CT
1-877-625-2566
1-888-752-7626 (Fax)
connect.mckesson.com
PUERTO RICO HOSPITALS AND CLINICS
Authorized Distributor Phone/Fax/Website
Cardinal Puerto Rico (Borschow) 1-787-625-4200
orderexpress.
cardinalhealth.com
Cesar Castillo, Inc. 1-787-641-5242
(Hospitals)
1-787-641-5082
(Specialty Pharmacies)
1-787-999-1614 (Fax)
www.facilfarmaciacci.com

Above information is accurate as of 04/22. The most updated distributors can be found on
https://www.bmsaccesssupport.bmscustomerconnect.com/reblozyl/billing-diagnosis-codes.

The REBLOZYL distribution program includes extended payment terms to Bristol Myers Squibb authorized REBLOZYL distributors. Healthcare providers and institutions should contact their REBLOZYL distributor to understand specific payment terms that may be available to them from their distributor.

NDCs and how supplied

NDC and packaging information

Product/
Strength
Package/
Description
11-Digit NDC
REBLOZYL injection 25 mg/vial 25-mg lyophilized powder for solution for injection in a single-dose vial for reconstitution 59572-0711-01
REBLOZYL injection 75 mg/vial 75-mg lyophilized powder for solution for injection in a single-dose vial for reconstitution 59572-0775-01

The red zero converts the 10-digit NDC to the 11-digit NDC. Payer requirements regarding the use of NDCs may vary. Electronic data exchange generally requires use of the 11-digit NDC.

Billing and coding

HCPCS codes
J0896 Injection, luspatercept-aamt, 0.25 mg
CPT® codes
96372 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); subcutaneous or intramuscular
96401
(for potential use only in MDS)
Chemotherapy administration, subcutaneous or intramuscular; non-hormonal anti-neoplastic
Billing units
1 unit = 0.25 mg 25-mg vial 100 units
75-mg vial 300 units
ICD-10-CM diagnosis codes for MDS
D46.1 Refractory anemia with ring sideroblasts
D46.A Refractory cytopenia with multilineage dysplasia
D46.B Refractory cytopenia with multilineage dysplasia and ring sideroblasts
D46.4 Refractory anemia, unspecified
D46.Z Other myelodysplastic syndromes
D46.9 Myelodysplastic syndrome, unspecified
ICD-10-CM diagnosis codes for beta-thalassemia
D56.1 Beta-thalassemia
  • Beta-thalassemia major
  • Cooley’s anemia
  • Homozygous beta-thalassemia
  • Severe beta-thalassemia
  • Thalassemia intermedia
  • Thalassemia major
D56.5 Hemoglobin E beta-thalassemia

CPT=Current Procedural Terminology; HCPCS=Healthcare Common Procedure Coding System; ICD-10-CM=International Classification of Diseases, Tenth Revision, Clinical Modification.

CPT® codes and descriptions are copyright 2020 American Medical Association (AMA). All rights reserved. CPT® is a registered trademark of the AMA.

The 2020 version of ICD-10-CM took effect on October 1, 2019.

The information contained herein is not intended to provide specific coding and reimbursement advice for any specific patient or situation. You should check with your coding specialist to ensure appropriate submissions.

REBLOZYL® reimbursement and coding guide thumbnail

Consult a reference guide for reimbursement and coding for REBLOZYL

The Reimbursement and Coding Guide provides coding, billing, and reimbursement information to support practice administrators.

Download the Guide

Patient Access, Reimbursement, and Co-Pay Support

Available Through

Bristol Myers Squibb is committed to helping appropriate patients initiate and maintain access to our medications during the treatment journey. That’s why we created BMS Access Support®, which offers benefits reviews, prior authorization assistance, and appeal process support, as well as an easy-to-initiate co-pay assistance process and information on financial support. The BMS Access Support Co-pay Assistance Program assists with out-of-pocket co-payment or co-insurance requirements for eligible, commercially insured patients who have been prescribed certain Bristol Myers Squibb products, including REBLOZYL. For more information, visit BMS Access Support, or call BMS Access Support at 1-800-861-0048, 8 AM to 8 PM ET, Monday-Friday.

Patient Access, Reimbursement, and Co-Pay Support

Available Through

At BMS, we provide support with purpose.

The BMS Access Support program is dedicated to helping patients access their prescribed BMS medications. We may offer benefit investigations, prior authorizations assistance, appeals process support, and information on financial support options. The BMS Access Support Co-Pay Assistance Program assists with out-of-pocket co-payment or co-insurance requirements for eligible, commercially-insured patients who have been prescribed certain BMS products, including REBLOZYL® (luspatercept-aamt).

For more information, visit BMS Access Support or call BMS Access Support at 1-800-861-0048, 8 am to 8 pm ET, Monday – Friday.

SUPPORT AND RESOURCES: ACCESS AND FINANCIAL RESOURCES

Authorized distributors

REBLOZYL can only be purchased through authorized distributors for administration in physician offices, hospital outpatient facilities, institutions, Veterans Affairs, and the Department of Defense. The following distributors are authorized to sell REBLOZYL and are able to service qualified accounts.

Authorized distributor network

PHYSICIAN OFFICES
Authorized Distributor Phone/Fax Website
Cardinal Health Specialty Pharmaceutical Distribution
Mon-Fri, 7:00 AM-6:00 PM CT
1-877-453-3972 specialtyonline.cardinalhealth.com
CuraScript Specialty Distribution
Mon-Fri, 8:00 AM-7:00 PM ET
1-877-599-7748 www.curascriptsd.com
McKesson Specialty Health
Mon-Fri, 7:00 AM-7:00 PM CT
1-800-482-6700 mscs.mckesson.com
Morris & Dickson Specialty
Mon-Fri, 8:00 AM-6:00 PM CT
1-800-710-6100
1-318-524-3096 (Fax)
www.mdspecialtydist.com
Oncology Supply
Mon-Fri, 8:00 AM-7:00 PM CT
1-800-633-7555 www.oncologysupply.com
HOSPITALS AND INFUSION CENTERS
Authorized Distributor Phone/Fax Website
ASD Healthcare
Mon-Thurs, 7:00 AM-6:30 PM CT;
Friday, 7:00 AM-6 PM CT
1-800-746-6273
1-800-547-9413 (Fax)
www.asdhealthcare.com
Cardinal Health Specialty Pharmaceutical Distribution
Mon-Fri, 7:00 AM-6:00 PM CT
1-866-677-4844
1-614-553-6301 (Fax)
orderexpress.cardinalhealth.com
DMS Pharmaceutical Group, Inc.
Mon-Fri, 8:30 AM-5:00 PM CT
1-877-788-1100
1-847-518-1105 (Fax)
www.dmspharma.com
McKesson Plasma and Biologics
Mon-Fri, 8:00 AM-6:30 PM CT
1-877-625-2566
1-888-752-7626 (Fax)
connect.mckesson.com
PUERTO RICO HOSPITALS AND CLINICS
Authorized Distributor Phone/Fax Website
Cardinal Puerto Rico (Borschow) 1-787-625-4200 orderexpress.cardinalhealth.com
Cesar Castillo, Inc. 1-787-641-5242 (Hospitals)
1-787-641-5082 (Specialty Pharmacies)
1-787-999-1614 (Fax)
www.facilfarmaciacci.com
PHYSICIAN OFFICES
Authorized Distributor Phone/Fax/Website
Cardinal Health Specialty Pharmaceutical Distribution
Mon-Fri, 7:00 AM-6:00 PM CT
1-877-453-3972
specialtyonline.
cardinalhealth.com
CuraScript Specialty Distribution
Mon-Fri, 8:00 AM-7:00 PM ET
1-877-599-7748
www.curascriptsd.com
McKesson Specialty Health
Mon-Fri, 7:00 AM-7:00 PM CT
1-800-482-6700
mscs.mckesson.com
Morris & Dickson Specialty
Mon-Fri, 8:00 AM-6:00 PM CT
1-800-710-6100
1-318-524-3096 (Fax)
www.mdspecialtydist.com
Oncology Supply
Mon-Fri, 8:00 AM-7:00 PM CT
1-800-633-7555
www.oncologysupply.com
HOSPITALS AND INFUSION CENTERS
Authorized Distributor Phone/Fax/Website
ASD Healthcare
Mon-Thurs, 7:00 AM-6:30 PM CT;
Friday, 7:00 AM-6 PM CT
1-800-746-6273
1-800-547-9413 (Fax)
www.asdhealthcare.com
Cardinal Health Specialty Pharmaceutical Distribution
Mon-Fri, 7:00 AM-6:00 PM CT
1-866-677-4844
1-614-553-6301 (Fax)
cardinalhealth.com
DMS Pharmaceutical Group, Inc.
Mon-Fri, 8:30 AM-5:00 PM CT
1-877-788-1100
1-847-518-1105 (Fax)
www.dmspharma.com
McKesson Plasma and Biologics
Mon-Fri, 8:00 AM-6:30 PM CT
1-877-625-2566
1-888-752-7626 (Fax)
connect.mckesson.com
PUERTO RICO HOSPITALS AND CLINICS
Authorized Distributor Phone/Fax/Website
Cardinal Puerto Rico (Borschow) 1-787-625-4200
orderexpress.
cardinalhealth.com
Cesar Castillo, Inc. 1-787-641-5242
(Hospitals)
1-787-641-5082
(Specialty Pharmacies)
1-787-999-1614 (Fax)
www.facilfarmaciacci.com

Above information is accurate as of 04/22. The most updated distributors can be found on
https://www.bmsaccesssupport.bmscustomerconnect.com/reblozyl/billing-diagnosis-codes.

The REBLOZYL distribution program includes extended payment terms to Bristol Myers Squibb authorized REBLOZYL distributors. Healthcare providers and institutions should contact their REBLOZYL distributor to understand specific payment terms that may be available to them from their distributor.

NDCs and how supplied

NDC and packaging information

Product/
Strength
Package/
Description
11-Digit NDC
REBLOZYL injection 25 mg/vial 25-mg lyophilized powder for solution for injection in a single-dose vial for reconstitution 59572-0711-01
REBLOZYL injection 75 mg/vial 75-mg lyophilized powder for solution for injection in a single-dose vial for reconstitution 59572-0775-01

The red zero converts the 10-digit NDC to the 11-digit NDC. Payer requirements regarding the use of NDCs may vary. Electronic data exchange generally requires use of the 11-digit NDC.

Billing and coding

HCPCS codes
J0896 Injection, luspatercept-aamt, 0.25 mg
CPT® codes
96372 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); subcutaneous or intramuscular
96401
(for potential use only in MDS)
Chemotherapy administration, subcutaneous or intramuscular; non-hormonal anti-neoplastic
Billing units
1 unit = 0.25 mg 25-mg vial 100 units
75-mg vial 300 units
ICD-10-CM diagnosis codes for MDS
D46.1 Refractory anemia with ring sideroblasts
D46.A Refractory cytopenia with multilineage dysplasia
D46.B Refractory cytopenia with multilineage dysplasia and ring sideroblasts
D46.4 Refractory anemia, unspecified
D46.Z Other myelodysplastic syndromes
D46.9 Myelodysplastic syndrome, unspecified
ICD-10-CM diagnosis codes for beta-thalassemia
D56.1 Beta-thalassemia
  • Beta-thalassemia major
  • Cooley’s anemia
  • Homozygous beta-thalassemia
  • Severe beta-thalassemia
  • Thalassemia intermedia
  • Thalassemia major
D56.5 Hemoglobin E beta-thalassemia

CPT=Current Procedural Terminology; HCPCS=Healthcare Common Procedure Coding System; ICD-10-CM=International Classification of Diseases, Tenth Revision, Clinical Modification.

CPT® codes and descriptions are copyright 2020 American Medical Association (AMA). All rights reserved. CPT® is a registered trademark of the AMA.

The 2020 version of ICD-10-CM took effect on October 1, 2019.

The information contained herein is not intended to provide specific coding and reimbursement advice for any specific patient or situation. You should check with your coding specialist to ensure appropriate submissions.

REBLOZYL® reimbursement and coding guide thumbnail

Consult a reference guide for reimbursement and coding for REBLOZYL

The Reimbursement and Coding Guide provides coding, billing, and reimbursement information to support practice administrators.

Download the Guide

Patient Access, Reimbursement, and Co-Pay Support

Available Through

Bristol Myers Squibb is committed to helping appropriate patients initiate and maintain access to our medications during the treatment journey. That’s why we created BMS Access Support®, which offers benefits reviews, prior authorization assistance, and appeal process support, as well as an easy-to-initiate co-pay assistance process and information on financial support. The BMS Access Support Co-pay Assistance Program assists with out-of-pocket co-payment or co-insurance requirements for eligible, commercially insured patients who have been prescribed certain Bristol Myers Squibb products, including REBLOZYL. For more information, visit BMS Access Support, or call BMS Access Support at 1-800-861-0048, 8 AM to 8 PM ET, Monday-Friday.

Patient Access, Reimbursement, and Co-Pay Support

Available Through

At BMS, we provide support with purpose.

The BMS Access Support program is dedicated to helping patients access their prescribed BMS medications. We may offer benefit investigations, prior authorizations assistance, appeals process support, and information on financial support options. The BMS Access Support Co-Pay Assistance Program assists with out-of-pocket co-payment or co-insurance requirements for eligible, commercially-insured patients who have been prescribed certain BMS products, including REBLOZYL® (luspatercept-aamt).

For more information, visit BMS Access Support or call BMS Access Support at 1-800-861-0048, 8 am to 8 pm ET, Monday – Friday.

References: 1. REBLOZYL [US Prescribing Information]. Summit, NJ: Celgene Corporation; 2023. 2. Data on file package: BMS-REF-ACE-536-0009. Princeton, NJ: Bristol-Myers Squibb Company; 2023.